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15-Hydroxyprostaglandin dehydrogenase and hexokinase in spontaneously hypertensive rat kidney

C N Corder, K J Bixenstine, A P Shapiro

Experientia

|December 15, 1984

Abstract:

15-Hydroxyprostaglandin dehydrogenase (PGDH) surged in hypertensive (SHR) and normotensive (WKY) rat kidney at 8 days of age, is greatest in SHR. Hexokinase fell in SHR at 17 days of age, but thereafter was similar to WKY. This suggests multisystem enzymatic abnormalities in SHR kidney during development of hypertension.

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