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Angina pectoris and blood lactate concentration during graded exercise
International Journal of Sports Medicine
|December 1, 1984
Summary
Chest pain intensity in angina pectoris patients correlates with blood lactate levels during exercise. This study found a near-linear relationship, suggesting lactate influences anginal pain perception.
Area of Science:
- Cardiology
- Exercise Physiology
- Pain Management
Background:
- Angina pectoris is a common condition requiring objective assessment.
- Understanding the physiological markers of anginal pain is crucial for patient management.
Purpose of the Study:
- To investigate the relationship between perceived anginal pain intensity and blood lactate levels during graded exercise.
- To explore potential causal links between metabolic changes and chest pain in patients with angina pectoris.
Main Methods:
- Nineteen patients with angina pectoris underwent graded exercise testing.
- Psychophysical scaling of chest pain (Borg scale) and blood lactate measurements were performed at rest and during exercise.
- Exercise was terminated at a rated anginal pain level of 5-6/9, defining Wmax.
Main Results:
- Heart rate at Wmax varied across patient groups categorized by Wmax.
- Perceived anginal pain intensity and blood lactate levels increased with exercise intensity.
- A near-linear relationship was observed between rated anginal pain and blood lactate levels across all groups.
Conclusions:
- Blood lactate accumulation appears to be a significant factor in the perception of anginal chest pain.
- The findings suggest a causal relationship between lactate and anginal pain, aiding in understanding pain mechanisms.
- This relationship could inform more targeted therapeutic strategies for angina pectoris management.