[Histogenesis of uterine corpus carcinoma--relation to atypical endometrial hyperplasia]

We have studied the histogenesis of uterine corpus carcinoma with special reference to the relation to endometrial atypical hyperplasia. The summary of the results is as follows. The subjects of the study were 113 cases of operated uterine corpus cancer and 2,440 of noncorporeal (uterine) cancer. Atypical hyperplasia of the residual endometrium in corpus carcinoma was revealed in 42 of the 113 cases (37.2%). Among 19 premenopausal patients, the residual endometrium was in the secretory phase in 3 and in the proliferative phase in the others. The site of its appearance was either in the functional or non-functional layers with diffuse (16) and localized (26) types. A malignant change from the atypical hyperplastic (hormone dependent ?) and atrophic endometrium (hormone independent ?) was suggested.