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Inhibition of acetate incorporation into lipids by adriamycin
Research Communications in Chemical Pathology and Pharmacology
|November 1, 1984
Abstract:
Adriamycin (ADM) inhibits 14C-acetate incorporation into cardiomyocytes, with the ID50 being 0.9 microM. Incorporation into neutral lipids were inhibited except for cholesterol ester. Cholesterol and phospholipids demonstrated the strongest inhibition at 5 microM ADM.
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