[Free amino acids in brain tissue and its subcellular structures in hyperthermia in rats]

Free amino acids reserves in the brain tissue, nuclei and mitochondria were investigated in mongrel albino rats under conditions of hyperthermia (45 degrees C) of different duration--7,20 and 60 min. It was found that reserves of most free amino acids in the albino rat brain decreased under a short-term (7 min) hyperthermia and accumulated under more prolonged (20-60 min) one. The amount of amino acids in the brain mitochondria increased 7 min after the experiment start and decreased 20 min later, then (60 min later) the amount of most amino acids increased considerably. Opposite shifts were detected in the content of most amino acids in nuclei.