[1-14C]acetate incorporation into free and esterified cholesterol during the development of the rat ventral prostate

The in vivo [1-14C]acetate incorporation into free and esterified cholesterol in rat ventral prostate depends on the animal developmental process, and it is the highest in the puberty stage. The relationship between free cholesterol and total lipids is 12-14% and that between esterified cholesterol and total lipids is 4-5%, both of the two being maintained during the animal development. The [1-14C]-acetate incorporation into free and esterified cholesterol in castrated animals decreases as compared with that in normal rats and it does not depend on the age of the animal.