Related Experiment Video
Updated: May 5, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
Published on: January 7, 2019
Late prosthetic valve endocarditis
Abstract:
A report is given of 13 patients with late prosthetic valve endocarditis (1975-1982). Follow-up ranged from 1 to 8 years (mean 33 months). Causative organisms were streptococci in 8 cases, staphylococci in 2, and Cardiobacterium hominis in 1. Cultures were negative in 2. Surgical treatment in the acute phase was performed in 3 patients. At the latest clinical control, 3 patients had died and 10 patients were asymptomatic, 3 of them having required late operation. These fair results are attributable to the particular spectrum of causative organisms and to the proper timing of surgical treatment in the 3 patients operated during the acute phase.
Insights
Late prosthetic valve endocarditis outcomes were studied in 13 patients. Early surgical intervention and specific causative organisms contributed to favorable results in most cases.
Area of Science:
- Cardiology
- Infectious Diseases
- Cardiac Surgery
Background:
- Late prosthetic valve endocarditis (PVE) poses significant challenges in patient management.
- Understanding causative organisms and treatment outcomes is crucial for improving patient survival.
Purpose of the Study:
- To report on the clinical course and outcomes of patients diagnosed with late prosthetic valve endocarditis.
- To identify factors influencing patient prognosis in late PVE.
Main Methods:
- Retrospective analysis of 13 patients with late PVE treated between 1975 and 1982.
- Evaluation of causative microorganisms, treatment strategies (medical and surgical), and patient follow-up data.
Main Results:
- Streptococci were the most common pathogens (8 cases), followed by staphylococci (2 cases).
- Three patients underwent acute-phase surgery, with 10 remaining asymptomatic at long-term follow-up.
- Mortality was observed in 3 patients, with 3 requiring late surgical intervention.
Conclusions:
- Favorable outcomes in late PVE can be achieved through timely surgical intervention during the acute phase.
- The specific spectrum of causative organisms, including streptococci, may influence treatment success.
- Careful patient selection and management are key to improving prognosis in late prosthetic valve endocarditis.
More Related Videos
05:31Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
06:59Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Stenosis III: Medical Management
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management