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Effective dose equivalent from radiopharmaceuticals.

L Johansson, S Mattsson, B Nosslin

    European Journal of Nuclear Medicine
    |January 1, 1984
    PubMed
    Summary
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    This study quantifies radiation risk in nuclear medicine by presenting effective dose equivalent values for various radiopharmaceuticals. These findings help nuclear medicine departments estimate patient radiation exposure and risk from diagnostic procedures.

    Area of Science:

    • Medical Physics
    • Radiological Protection
    • Nuclear Medicine

    Background:

    • The effective dose equivalent, established by the ICRP for occupational exposure, offers a method to quantify radiation risk in medical imaging.
    • Assessing radiation risk to patients undergoing radiodiagnostic procedures is crucial for optimizing safety.

    Purpose of the Study:

    • To present the effective dose equivalent for a range of nuclear medicine investigations.
    • To provide a basis for estimating patient radiation risk in nuclear medicine.

    Main Methods:

    • Literature review of mean absorbed doses to organs.
    • In-house calculations using biokinetic data from scientific literature.

    Main Results:

    • Effective dose equivalent per activity unit administered varies widely across radiopharmaceuticals (0.00015 to 20 mSv/MBq).

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  • Technetium-labelled compounds show a narrower range for absorbed dose (0.0060 to 0.025 mSv/MBq) for 90% of substances.
  • Conclusions:

    • The presented data enables nuclear medicine departments to estimate effective dose equivalent and patient radiation risk.
    • Standardized risk assessment can be improved through the application of these dose equivalent figures.