Hypertrophic osteoperiostitis in Crohn's disease

The authors present a case of hypertrophic osteoperiostitis in a patient suffering from Crohn's disease. A review of the literature reveals 10 cases of Crohn's disease or ulcerative colitis with similar affections of the skeletal system, some of which were asymptomatic. This supports the hypothesis that the immunological phenomena which are common to both these intestinal diseases are also the basis of the skeletal affection.