Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypoxemia increases plasma catecholamine concentrations in exercising humans.

P Escourrou, D G Johnson, L B Rowell

    Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
    |November 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comparison of under-mattress sensor and CPAP data for home monitoring in obstructive sleep apnea.

    Sleep & breathing = Schlaf & Atmung·2026
    Same author

    Contrasting effects of an Mdm2 functional polymorphism on tumor phenotypes.

    Oncogene·2017
    Same author

    NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration.

    Neuroscience·2014
    Same author

    Determination of the primary charge separation rate in Photosystem II reaction centers at 15 K.

    Photosynthesis research·2014
    Same author

    Short communication: Jersey × Holstein crossbreds compared with pure Holsteins for body weight, body condition score, fertility, and survival during the first three lactations.

    Journal of dairy science·2012
    Same author

    The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories.

    The European respiratory journal·2011

    During exercise with hypoxemia, plasma norepinephrine and epinephrine levels significantly increase, reflecting sympathetic nervous activity (SNA). These elevated catecholamine concentrations exceed thresholds for direct physiological effects in normoxic conditions.

    Area of Science:

    • Exercise Physiology
    • Cardiovascular Physiology
    • Neuroendocrinology

    Background:

    • Sympathetic nervous activity (SNA) is crucial during exercise.
    • Hypoxemia (low oxygen) can influence physiological responses to exercise.
    • Understanding catecholamine responses to exercise under hypoxemia is important for performance and health.

    Purpose of the Study:

    • To investigate plasma catecholamine concentrations during exercise in hypoxemic conditions.
    • To compare sympathetic nervous activity (SNA) during exercise in normoxia versus hypoxemia.
    • To determine if hypoxemia alters the relationship between catecholamines, heart rate, and exercise intensity.

    Main Methods:

    • Seven healthy men performed graded exercise tests (40-88% VO2max) under normoxic and hypoxemic (11-12% O2) conditions.

    Related Experiment Videos

  • Plasma norepinephrine (NE) and epinephrine (E) concentrations were measured using a radioenzyme technique.
  • Relationships between plasma catecholamines, heart rate (HR), and maximal oxygen uptake (VO2max) were analyzed.

    • Main Results:

    • Hypoxemia significantly elevated plasma NE and E concentrations at all exercise intensities compared to normoxia.
    • Plasma NE levels increased substantially with exercise intensity under hypoxemia.
    • Despite elevated catecholamines, the relationship between NE, HR, and VO2max remained linear, suggesting NE reflects relative exercise intensity and SNA.

    Conclusions:

    • Plasma catecholamine concentrations rise significantly above normoxic levels during exercise with hypoxemia.
    • Elevated NE and E during hypoxemic exercise may exceed levels with direct physiological effects.
    • Hypoxemia may modulate vasoconstrictive responses despite high catecholamine levels.