Epiandrosterone- and dehydroepiandrosterone-3 beta-alkanesulfonates as inhibitors of mouse glucose-6-phosphate...

3 beta-Alkanesulfonates of dehydroepiandrosterone, 16 alpha-bromodehydroepiandrosterone, epiandrosterone, and 16 alpha-bromoepiandrosterone were prepared in 54-95% yield via the reaction of long chain alkanesulfonyl chlorides with the corresponding dehydroepiandrosterone, and epiandrosterone analogues. These compounds inhibit mouse glucose-6-phosphate dehydrogenase activity.