Calcinosis circumscripta in two rhesus monkeys

Firm multilobular subcutaneous masses were observed in two female rhesus monkeys (Macaca mulatta). Both masses were excised surgically, but reoccurred within three months. Histologically, multiple loculi of calcified material surrounded by inflammatory cells and fibrous tissue were apparent. A diagnosis of calcinosis circumscripta was made. The gross and histologic appearance of this disease resembles that reported in several species.