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Heterochromatinization as a key factor in aging
Mechanisms of Ageing and Development
|December 1, 1984
Abstract:
An analysis of observations on modifications during aging of the characteristics of chromosomes during the mitotic cycle of their mutations and unscheduled aging leads to the conclusion that enhanced heterochromatinization during aging prevents the action of reparative enzymes, and results in increased numbers of cells with chromosomal aberrations.