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Updated: Aug 12, 2026

An Introduction to Worm Lab: from Culturing Worms to Mutagenesis
Published on: January 11, 2011
Study of mutagenic pollution in Bombay
Abstract:
Airborne suspended particulate matter (SPM) from seven areas in and around Bombay city were collected over glass fibre filters (0.8 micrometer porosity). The chemicals from the SPM were extracted in dimethylsulfoxide and distilled water and were further tested for mutagenicity by Ames' test using for five mutants of Salmonella typhimurium. Of the seven areas studied, only four exhibited mutagenicity, which was confirmed by dose-response assays using the mutant strain TA 100. The very high mutagenicity observed in central Bombay correlates with the higher incidence of respiratory tract diseases in the resident population.
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