Thiamphenicol in the treatment of extragenital gonorrhea

One hundred ninety-two cases of gonorrhea, of which 23 were extragenital only or both genital and extragenital, were treated with a single oral dose of thiamphenicol (2.5 g in patients weighing less than or equal to 80 kg; 3 g in patients weighing greater than 80 kg). Of the 178 patients whose follow-up was possible, 176 patients (98.9%), including all 23 with extragenital infection (seven pharyngeal and 16 anorectal), recovered completely. The efficacy of the regimen compared favorably with that of other regimens currently used for the treatment of gonorrhea.