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Updated: Aug 17, 2026

Fluorescence in situ hybridization (FISH) Protocol in Human Sperm
Published on: September 1, 2009
[Sperm anomalies and their significance for the diagnosis of spermatogenesis disorders]
Abstract:
In this paper, morphological abnormalities of spermatozoa in the seminal fluid smear are described. An advantageous classification seems to be recommended: disturbances of the head, the cap, the midpiece, and the tail. The knowledge of intratesticular spermatogenetic processes and their disorders in certain phases of sensitivity enables the description of the disturbances of the spermium itself and beyond a systematical classification of pathological spermatozoon formation in relation to the kind or to the period of their origin. We recommend this method of sterility diagnosis as a alternative method to the testicular biopsy, because the last investigation is loading the patient.
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