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[Pneumococcal serotypes in various diseases of children]

A L Vinnik, O I Stenina, T A Dudina

    Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
    |November 1, 1984
    PubMed

    Insights

    This study identified 11 pneumococcal serotypes in children, with serotypes 3, 6, 9, and 19 being most common. Most strains remained sensitive to penicillin antibiotics.

    Area of Science:

    • Microbiology
    • Pediatrics
    • Infectious Diseases

    Background:

    • Pneumococcal infections pose a significant threat to children's health.
    • Understanding the serotype distribution and antibiotic susceptibility of pneumococci is crucial for effective disease management and prevention.

    Purpose of the Study:

    • To serotype pneumococci isolated from children aged 0-11 years with various diseases.
    • To determine the etiological role of pneumococci in disease pathogenesis.
    • To assess the antibiotic susceptibility of isolated pneumococcal strains.

    Main Methods:

    • Serotyping of pneumococcal isolates from clinical samples of 156 pediatric patients.
    • Quantitative inoculation methods to establish etiological significance.
    • Antibiotic susceptibility testing against penicillin, ampicillin, and benzylpenicillin.

    Main Results:

    • Pneumococci were isolated from 43% (67/156) of patients.
    • Eleven distinct pneumococcal serotypes were identified.
    • Serotypes 3, 6, 9, and 19 were the most prevalent, accounting for 50% of isolates.
    • A correlation between pneumococcal serotype diversity and children's age was observed.
    • The majority of isolated strains exhibited sensitivity to penicillin, ampicillin, and benzylpenicillin.

    Conclusions:

    • Specific pneumococcal serotypes are frequently associated with pediatric diseases.
    • Quantitative methods can elucidate the role of pneumococci in disease.
    • Age influences pneumococcal serotype distribution in children.
    • Pneumococci isolated in this study largely remained susceptible to common penicillin-based antibiotics.

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