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Related Experiment Videos

Placenta flow reduction in pregnant smokers.

K V Andersen, N Hermann

    Acta Obstetricia Et Gynecologica Scandinavica
    |January 1, 1984
    PubMed
    Summary

    Smoking during pregnancy significantly reduces placental blood flow and infant birth weight. These detrimental effects appear to be permanent, underscoring the need for smoking cessation advice for expectant mothers.

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    Area of Science:

    • Obstetrics and Gynecology
    • Perinatology
    • Maternal-Fetal Medicine

    Background:

    • Maternal smoking is a known risk factor for adverse pregnancy outcomes.
    • The precise impact of smoking on placental perfusion remains an area of investigation.

    Purpose of the Study:

    • To quantify intervillous space placental perfusion in pregnant smokers versus non-smokers.
    • To investigate the correlation between placental perfusion and infant birth weight in these groups.

    Main Methods:

    • Radio-isotope method used to measure placental perfusion in 46 pregnant women (23 smokers, 23 non-smokers) between 33-37 weeks gestation.
    • Groups were matched for essential variables, including normotension.

    Main Results:

    • Significantly lower placental perfusion observed in pregnant smokers compared to non-smokers.
    • Infants born to smokers exhibited significantly lower birth weights.
    • A positive correlation between placental perfusion and birth weight was noted in both groups.

    Conclusions:

    • Smoking during pregnancy leads to chronic, potentially permanent, reductions in intervillous placental blood flow.
    • These findings support strong recommendations against smoking during pregnancy to improve fetal outcomes.

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