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Susceptibility of Bacteroides from swine abscesses to 13 antibiotics

Y Benno, T Mitsuoka

    American Journal of Veterinary Research
    |December 1, 1984
    PubMed

    Insights

    Clindamycin demonstrated the highest activity against Bacteroides strains from pig abscesses. Most isolates were susceptible to several antibiotics, but resistance to streptomycin and neomycin was observed.

    Area of Science:

    • Veterinary Microbiology
    • Antimicrobial Resistance
    • Bacteriology

    Background:

    • Bacteroides species are significant pathogens in animal infections, particularly abscesses.
    • Understanding antimicrobial susceptibility is crucial for effective treatment of these infections.

    Purpose of the Study:

    • To determine the antimicrobial susceptibility profiles of Bacteroides strains isolated from pig abscesses.
    • To evaluate the efficacy of 13 different antimicrobial agents against these isolates.

    Main Methods:

    • Agar-dilution method was employed under anaerobic conditions.
    • Minimal inhibitory concentrations (MICs) were determined for 129 Bacteroides strains.
    • Thirteen distinct antimicrobial agents were tested.

    Main Results:

    • Clindamycin exhibited the highest activity, with a median MIC of 0.8 µg/ml.
    • Penicillin G, talampicillin, minocycline, chloramphenicol, and cefoxitin were effective against all isolates at low concentrations.
    • Some strains showed susceptibility to gentamicin, erythromycin, and cephalexin, while resistance to streptomycin and neomycin was noted.

    Conclusions:

    • Clindamycin is a highly effective agent against Bacteroides from pig abscesses.
    • Several other antibiotics show promise, but resistance patterns necessitate careful selection.
    • Further surveillance of antimicrobial resistance in veterinary pathogens is warranted.

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