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Angle-closure glaucoma: relation between lens thickness, anterior chamber depth and age
Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|December 1, 1984
Summary
Lens growth patterns in primary angle-closure glaucoma (ACG) show abnormal thickening, contributing to shallow anterior chambers. Acute ACG attacks peak during specific age ranges, avoiding periods of stable lens growth.
Area of Science:
- Ophthalmology
- Biometry
- Glaucoma Research
Background:
- Primary angle-closure glaucoma (ACG) is a significant cause of vision loss.
- Understanding the ocular biometric changes associated with ACG progression is crucial for effective management.
Purpose of the Study:
- To investigate the relationship between ultrasonographic biometric measurements and the occurrence of acute attacks in primary angle-closure glaucoma.
- To analyze the growth patterns of the lens and anterior chamber depth in relation to ACG.
Main Methods:
- Ultrasonographic biometric measurements, including axial length, lens thickness, and anterior chamber depth, were performed on 89 eyes with ACG.
- Analysis focused on mean values and age-related changes in these parameters.
Main Results:
- An abnormal lens growth pattern was observed, with accelerated thickening in the fourth to sixth decades, followed by a plateau and then slower growth.
- Anterior chamber depth consistently decreased at a steady rate.
- Acute ACG attacks showed two peaks: ages 53-58 and 63-70, with no attacks during the decade of stable lens growth.
Conclusions:
- Forward lens movement, possibly due to zonular loosening, contributes to anterior chamber shallowing in ACG.
- Lens growth dynamics and anterior chamber depth changes are implicated in the age-related incidence of acute ACG attacks.