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Preparation of a 211At-IgG conjugate which is stable in vivo
The International Journal of Applied Radiation and Isotopes
|November 1, 1984
The short lived (t 1/2 7.2 h) alpha-particle emitting halogen 211At has been attached to an antibody by using an acylation reaction to conjugate para-[211At]astato-benzoic acid with rabbit IgG. The conjugate, which is stable in vivo, contains at least 30% of the initial activity of 211At.
The short lived (t 1/2 7.2 h) alpha-particle emitting halogen 211At has been attached to an antibody by using an acylation reaction to conjugate para-[211At]astato-benzoic acid with rabbit IgG. The conjugate, which is stable in vivo, contains at least 30% of the initial activity of 211At.