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Updated: Aug 17, 2026

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High-throughput Crystallization of Membrane Proteins Using the Lipidic Bicelle Method
Published on: January 9, 2012
Crystalline monoclonal antibody Fabs complexed to hen egg white lysozyme
Journal of Molecular Biology
|December 15, 1984
Abstract:
The Fab of a monoclonal anti-lysozyme antibody (HyHEL-10) has been crystallized as the free Fab and as the Fab-antigen complex. Crystals have also been grown of the antigen complex of the Fab of another monoclonal anti-lysozyme antibody (HyHEL-9), which recognizes a different binding surface of lysozyme. All three crystals diffract to at least 3 A resolution and are suitable for X-ray diffraction studies.
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