[Clinicopathological study of breast cancers associated with other primary cancers]

Thirty six cases of breast cancer associated with other primary cancer were found out among 1160 patients with primary breast cancer. They consisted of 6 synchronous combination and 30 metachronous, in which 23 were detected as the first lesion and 7 were the second. The other organs involved by cancer were the stomach (11), thyroid (9), colon or rectum (5), uterus (3), and others (8). Although the TNM stage of the breast cancer was mostly in stage I or II (91.6%), the prognosis was poor in the metachronous cases, depending on the nature of the second primary cancer. It is important to detect and treat a second primary cancer in the early stage.