Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Methadone detoxification: self versus physician regulation.

E C Senay, W Dorus, C Showalter

    The American Journal of Drug and Alcohol Abuse
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Fantasies about the fetus in wanted and unwanted pregnancies.

    Journal of youth and adolescence·2014
    Same author

    A postmarketing surveillance program to monitor Ultram (tramadol hydrochloride) abuse in the United States.

    Drug and alcohol dependence·2000
    Same author

    Interventions/Wilmer: a continuum of care for substance abusers in the criminal justice system.

    Journal of psychoactive drugs·1995
    Same author

    Medical maintenance: an interim report.

    Journal of addictive diseases·1994
    Same author

    Medical maintenance: a pilot study.

    Journal of addictive diseases·1993
    Same author

    Low prevalence of sexual transmission of hepatitis C virus in sex partners of seropositive intravenous drug users.

    The Journal of infectious diseases·1991

    Physician-regulated or self-regulated methadone detoxification for heroin dependence showed no significant differences in abstinence rates or treatment outcomes. Self-regulation led to more dose increases, but overall effectiveness was comparable.

    Area of Science:

    • Addiction Medicine
    • Pharmacology
    • Clinical Psychology

    Background:

    • Opioid dependence is a significant public health issue.
    • Methadone maintenance is a common treatment for heroin dependence.
    • Detoxification regimens vary, with questions about optimal regulation strategies.

    Purpose of the Study:

    • To compare the effectiveness of physician-regulated versus self-regulated methadone detoxification.
    • To assess outcomes including abstinence rates, treatment retention, and symptom severity.

    Main Methods:

    • 108 heroin-dependent patients stabilized on methadone were studied.
    • Patients were divided into those preferring physician or self-regulation.
    • Half of each preference group was randomly assigned to either regulation type.

    Related Experiment Videos

  • Outcomes were assessed over a 22-week regimen.

    • Main Results:

    • No statistically significant difference in abstinence rates between physician and self-regulation groups.
    • No observed differences in treatment retention, symptom severity, drug test results, or psychosocial functioning.
    • Patients preferring self-regulation showed a statistically significant increase in methadone dose raises.

    Conclusions:

    • Current evidence does not support the superiority of physician regulation over self-regulation in methadone detoxification.
    • Both regulation approaches appear to yield similar outcomes for opioid detoxification.
    • Patient preference may influence dose adjustment patterns during detoxification.