Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Digestive localizations of scleroderma].

R Modigliani

    Annales De Medecine Interne
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Systemic scleroderma commonly affects the gastro-intestinal tract, causing motility disorders like reflux, dysphagia, and constipation. Treatment focuses on managing these symptoms, as there is no cure.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A randomized, double-blind, placebo-controlled trial of olsalazine for active Crohn's disease.

    Inflammatory bowel diseases·2013
    Same author

    Recommendations for New Trials of Currently Available Therapy by the IOIBD Task Force on Clinical Trials*.

    Inflammatory bowel diseases·2013
    Same author

    Drug Trials in Inflammatory Bowel Diseases 1993-1995: A Survey Conducted by the IOIBD.

    Inflammatory bowel diseases·2013
    Same author

    Clinical features of inflammatory bowel disease.

    Current opinion in gastroenterology·2006
    Same author

    Corticosteroids for maintenance of remission in Crohn's disease.

    The Cochrane database of systematic reviews·2003
    Same author

    Hydrostatic balloon dilatation of Crohn's strictures.

    Alimentary pharmacology & therapeutics·2003
    Same journal

    [Consensus Development Conference on Thrombosis and Pregnancy. 14 March 2003, Paris, France. Proceedings].

    Annales de medecine interne·2004
    Same journal

    Kartagener's syndrome and renal failure.

    Annales de medecine interne·2004
    Same journal

    Inflammatory pseudotumor of lymph nodes.

    Annales de medecine interne·2004
    Same journal

    [Necrolytic migratory erythema revealing glucagonoma without diabetes].

    Annales de medecine interne·2004
    Same journal

    [Bilateral primary non-Hodgkin's lymphomas of the adrenals].

    Annales de medecine interne·2004
    Same journal

    [Acute "pseudo-angiocholitis" due to colonic adenocarcinoma in a man with primary sclerosis cholangitis and ulcerative colitis].

    Annales de medecine interne·2004
    See all related articles

    Area of Science:

    • Gastroenterology
    • Rheumatology
    • Pathology

    Context:

    • Systemic scleroderma, a collagen vascular disease, frequently impacts the gastro-intestinal (GI) tract.
    • Over 50% of patients experience GI involvement, with the esophagus, small intestine, colon, and stomach being primary targets.

    Purpose:

    • To detail the mechanisms and clinical manifestations of gastro-intestinal involvement in systemic scleroderma.
    • To outline the spectrum of GI complications and current symptomatic treatment strategies.

    Summary:

    • GI symptoms stem from motility disorders due to nerve damage, smooth muscle atrophy, and fibrous infiltration.
    • Manifestations include esophageal reflux, dysphagia, small intestinal pseudo-obstruction, malabsorption, severe constipation, and acute abdominal emergencies like obstruction or infarction.

    Related Experiment Videos

  • Treatment is symptomatic, addressing reflux complications and malabsorption with antibiotics.

    • Impact:

    • Highlights the significant GI burden of systemic scleroderma, emphasizing motility dysfunction as the core issue.
    • Underscores the need for targeted symptomatic management of diverse GI complications in scleroderma patients.