Lymphocytes migration into membrane filters: divergent effects of syngeneic mouse serum and lymph

In the present paper, the effects of mouse serum and lymph in lymphocyte adhesion versus locomotion was distinguished using the same substrate (cellulose acetate filters) permissive (8 microns) and non-permissive (0.45 microns) to cells. The results presented suggest that serum and lymph have similar effects on lymphocyte adhesion, but behave differently in locomotion assays. The relevance of these findings to the understanding of the role of lymph proteins in the control of lymphocyte recirculation is discussed.