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[Surgery of vesico-ureteral reflux: results on infections]
Abstract:
Thirty five patients operated between january 1978 and december 1982 at the Clinique Urologique de l'Hôpital Cochin has suffered of recurrent urinary tract infection (UIT); 30 of them had had acute pyelonephritis. After surgery 30 patients have no longer any reflux (homo- or controlateral). Seven of them keep lower UTI, one has had 1 attack of acute pyelonephritis. Nine records had to been rejected. These results are in accordance with the medical literature: the surgical treatment of reflux prevents nearly all acute pyelonephritis and about two third of lower UTI.
Insights
Surgical treatment for refluxing urinary tract infections (UTI) effectively prevents acute pyelonephritis in most patients. This intervention also significantly reduces the occurrence of lower UTIs, improving patient outcomes and quality of life.
Area of Science:
- Urology
- Pediatric Surgery
- Infectious Diseases
Context:
- Recurrent urinary tract infections (UTI) pose a significant clinical challenge, particularly in patients with vesicoureteral reflux.
- Acute pyelonephritis, a severe form of UTI, can lead to long-term renal damage.
- Surgical intervention for vesicoureteral reflux has been explored as a method to mitigate recurrent infections.
Purpose:
- To evaluate the efficacy of surgical treatment in managing recurrent urinary tract infections (UTI) and associated acute pyelonephritis.
- To assess the long-term outcomes of surgical correction of vesicoureteral reflux.
- To determine the impact of surgery on the incidence of both lower UTIs and upper UTIs (acute pyelonephritis).
Summary:
- A cohort of 35 patients with recurrent UTI, 30 with prior acute pyelonephritis, underwent surgery for vesicoureteral reflux between 1978 and 1982.
- Post-operatively, 30 patients were free of reflux. Seven patients continued to experience lower UTIs, and one had a single episode of acute pyelonephritis.
- The study indicates that surgical treatment for reflux significantly prevents acute pyelonephritis and reduces lower UTI rates by approximately two-thirds.
Impact:
- Surgical correction of vesicoureteral reflux is a highly effective strategy for preventing recurrent acute pyelonephritis.
- The procedure offers substantial benefits in reducing the overall burden of urinary tract infections, including lower tract infections.
- These findings support the established medical literature on the positive impact of reflux surgery on UTI management and renal preservation.