[Correlation between diffuse alpha wave pattern of EEG and hyperfrontal pattern of regional cerebral blood flow]

Regional cerebral blood flow (rCBF) was measured in three groups; (1) 20 healthy subjects, (2) 14 patients with diffuse alpha wave pattern of EEG, (3) 14 patients without diffuse alpha wave pattern matching with ages of group 2. In the group 2, one patient with transient ischemic attack, 7 with reversible ischemic neurological deficit, 3 with vertebro-basilar insufficiency, 2 with minor stroke and one with posttraumatic sequelae were selected for rCBF measurements. In the group 3, 3 patients with transient ischemic attack, 7 with reversible ischemic neurological deficit, 2 with vertebro-basilar insufficiency and 2 with minor stroke were selected for rCBF measurements. Electroencephalographic analyses were performed by using a BERG-Fourier Analyzer, simultaneously with rCBF measurements. All patients in the group 2 had diffuse alpha wave (generalized continuous simple rhythmic alpha wave--Hori et al) pattern of EEG. Regional cerebral blood flow measurement was performed with intracarotid injection method of 133Xe (10 mCi) by using the scintillation camera and on-line computer system. 133Xe clearance curve from the whole hemisphere were computed by height over area method. Regional value were obtained from brain areas of 6 mm X 6 mm. Mean hemispheric values were 59.2 +/- 7.9 ml/100 g/min in the group 1, 47.8 +/- 4.9 ml/100 g/min in the group 2 and 49.0 +/- 3.7 ml/100 g/min in the group 3. Although difference between group 2 and 3 was not significant, difference between group 1 and 2 was significant (p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)