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[Intramuscular premedication with diazepam in a fat emulsion]
10 mg of diazepam in fat emulsion was given for premedication intramuscularly to 106 patients. In 53% of the cases patients were well sedated, 33% were apprehensive, 14% anxious. Pain related to the injection was complained of by 4 patients. Plasma concentration of diazepam at induction (60 minutes after the injection) was 130 ng/ml. Compared to diazepam in propylene glycol, pain at the injection side was less frequent while the level of sedation and the plasma concentration of diazepam were similar.
10 mg of diazepam in fat emulsion was given for premedication intramuscularly to 106 patients. In 53% of the cases patients were well sedated, 33% were apprehensive, 14% anxious. Pain related to the injection was complained of by 4 patients. Plasma concentration of diazepam at induction (60 minutes after the injection) was 130 ng/ml. Compared to diazepam in propylene glycol, pain at the injection side was less frequent while the level of sedation and the plasma concentration of diazepam were similar.