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Renal candidiasis in infancy--a case with fungus ball obstruction
Abstract:
A sixteen day old infant developed candiduria after surgery on a single functioning, hydronephrotic kidney with ureteropelvic junction stenosis. Masses of candida albicans caused obstruction of the ureter with acute anuria. Endoscopic relief of the obstruction together with aggressive antifungal therapy led to irradication of the fungal infection. This case history emphasizes the fact that candida infection in early childhood should be evaluated carefully. Unfortunately no guidelines are yet available for the indications and the preferred mode of treatment, and length of therapy of infantile renal candidiasis.
Insights
A pediatric case of severe candiduria in an infant caused ureteral obstruction and anuria. Prompt endoscopic intervention and antifungal treatment successfully eradicated the fungal infection, highlighting the need for careful evaluation of infant candidiasis.
Area of Science:
- Pediatric Nephrology
- Mycology
- Infectious Diseases
Background:
- Neonatal candiduria can lead to severe complications.
- Ureteropelvic junction stenosis is a congenital anomaly affecting kidney drainage.
- Surgical intervention in infants with renal anomalies may increase infection risk.
Observation:
- A 16-day-old infant with a single, hydronephrotic kidney and ureteropelvic junction stenosis developed candiduria post-surgery.
- Fungal masses (Candida albicans) obstructed the ureter, causing acute anuria.
- The infant presented with signs of severe urinary tract obstruction due to fungal growth.
Findings:
- Endoscopic relief of ureteral obstruction was performed.
- Aggressive antifungal therapy was administered.
- Successful eradication of the Candida albicans infection was achieved.
Implications:
- This case underscores the importance of thorough evaluation of Candida infections in neonates.
- There is a lack of established guidelines for treating infantile renal candidiasis.
- Further research is needed to define treatment indications, modalities, and duration for neonatal fungal kidney infections.