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Related Experiment Videos

Ventricular function in thyrotoxicosis complicated by atrial fibrillation.

A P Nisbet, S V Ellam, M N Maisey

    Nuclear Medicine Communications
    |March 1, 1984
    PubMed
    Summary

    Thyrotoxic atrial fibrillation, often linked to hyperthyroidism, does not appear to stem from underlying ischaemic heart disease. This finding suggests that further cardiac investigations may not be necessary for patients with this specific heart rhythm condition.

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    Area of Science:

    • Cardiology
    • Endocrinology
    • Nuclear Medicine

    Background:

    • Atrial fibrillation is a common arrhythmia.
    • Thyrotoxicosis, a state of excess thyroid hormones, is known to precipitate atrial fibrillation.
    • The relationship between thyrotoxic atrial fibrillation and underlying ischaemic heart disease requires clarification.

    Purpose of the Study:

    • To investigate the association between atrial fibrillation induced by thyrotoxicosis and the presence of underlying ischaemic heart disease.
    • To determine if ischaemic heart disease is a common comorbidity in patients experiencing thyrotoxic atrial fibrillation.

    Main Methods:

    • Utilized radionuclide gated ventriculography to assess cardiac function and structure.
    • Compared a cohort of ten patients with thyrotoxic atrial fibrillation (which resolved upon achieving a euthyroid state) to ten age-matched controls with treated hyperthyroidism without atrial fibrillation.

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    Main Results:

    • No significant difference was observed in the incidence of underlying ischaemic heart disease between the thyrotoxic atrial fibrillation group and the control group.
    • This indicates that ischaemic heart disease is not a distinguishing factor in patients with reversible thyrotoxic atrial fibrillation.

    Conclusions:

    • Simple, reversible atrial fibrillation associated with thyrotoxicosis is unlikely to be caused by underlying coronary arterial disease.
    • Routine investigation for coronary arterial disease is not recommended in such cases, potentially avoiding unnecessary procedures.