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Cholelithiasis in a preterm infant.

I Jeffrey, R J Lund, A Whitelaw

    Pediatric Pathology
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    A preterm infant developed gallbladder stones (cholelithiasis) after receiving multiple blood transfusions. This case suggests excessive bilirubin from high hemoglobin levels may cause pigment stones in neonates.

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    Area of Science:

    • Neonatal Medicine
    • Pediatric Gastroenterology
    • Pathology

    Background:

    • Cholelithiasis, or gallstones, is rare in preterm infants.
    • Neonatal hyperbilirubinemia can occur due to various factors, including blood transfusions.
    • Maintaining elevated hemoglobin levels in preterm infants is a common clinical practice.

    Observation:

    • A preterm infant survived for 105 days with multiple blood transfusions.
    • Necropsy revealed three pigment stones in the infant's gallbladder.

    Findings:

    • The presence of pigment stones suggests a link to excessive bilirubin.
    • Elevated bilirubin load, potentially from maintaining high hemoglobin levels, is implicated.

    Implications:

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    • This case highlights a potential risk of cholelithiasis in preterm infants receiving transfusions.
    • Clinical practices regarding hemoglobin management in neonates may warrant further investigation.
    • Understanding the etiology of gallstones in this population is crucial for preventative strategies.