[Evaluation of the results of treatment of endodermal sinus tumor in children]

Endodermal sinus tumor is a rare kind of cancer in children. In Clinical Department of Pediatric Oncology there were treated 8 children with endodermal sinus tumor (EST). 4 of them were localised in sacrococcygeal region, 3 in genital system and 1 in testis. In all these cases high level of AFP was observed. Complex therapy was done including surgery, chemotherapy and rtg-therapy, giving as result 3 years survival in 1 only case. Another case is still in course of the treatment. Unified protocol of therapy is not founded till now and prognosis in majority of children is not satisfied.