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Related Experiment Videos

Nummular thioridazine retinopathy.

D Kozy, B H Doft, J Lipkowitz

    Retina (Philadelphia, Pa.)
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Nummular thioridazine retinopathy, a rare condition, presents with distinct retinal changes in the periphery. These findings can occur even with previously safe doses of thioridazine.

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    Area of Science:

    • Ophthalmology
    • Retinal Diseases
    • Toxic Retinopathy

    Background:

    • Thioridazine retinopathy is a known condition.
    • Nummular thioridazine retinopathy is a unique clinical subset with limited documentation.
    • Previous reports documented only five cases of nummular thioridazine retinopathy.

    Observation:

    • This report details three additional cases of nummular thioridazine retinopathy.
    • Clinical features include nummular areas of retinal pigment epithelial atrophy.
    • These changes are observed in the midretinal periphery, sparing central vision.

    Findings:

    • Nummular areas of retinal pigment epithelial atrophy are separated by relatively intact pigment epithelium.
    • Central vision is spared in patients with nummular thioridazine retinopathy.

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  • This condition can manifest at thioridazine doses previously considered safe.

    • Implications:

    • The findings expand the understanding of nummular thioridazine retinopathy.
    • It highlights the potential for retinal toxicity at lower thioridazine doses than previously thought.
    • Ophthalmologists should be aware of these specific retinal findings in patients taking thioridazine.