Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Antibody deficiency without decrease in the level of serum immunoglobulins].

G Bellon, J L Touraine, R Gilly

Archives Francaises De Pediatrie

|December 1, 1984

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Intercomparison of methods of coupling between convection and large-scale circulation: 1. Comparison over uniform surface conditions.

Journal of advances in modeling earth systems·2016

Same author

Intercomparison of methods of coupling between convection and large-scale circulation: 2. Comparison over nonuniform surface conditions.

Journal of advances in modeling earth systems·2016

Same author

Analytical methods for measuring collagen XIX in human cell cultures, tissue extracts, and biological fluids.

Analytical biochemistry·2013

Same author

[Late onset Ondine syndrome: literature review on a case report].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2012

Same author

[Cystic fibrosis: centers and care networks organization].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2012

Same author

[Intrafamilial transmission of Staphylococcus aureus Panton-Valentine leukocidin responsible for two cases of neonatal necrotizing pneumonia].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2011

Same journal

A case of congenital myatonia (Oppenheim's disease).

Archives francaises de pediatrie·2010

Same journal

A case of severe haemolytic anemia anemia.

Archives francaises de pediatrie·2010

Same journal

On the acute anemia of the newborn.

Archives francaises de pediatrie·2010

Same journal

Intermittent jaundice; intrahepatic bile duct agenesis.

Archives francaises de pediatrie·2010

Same journal

Osteomyelitis with acute staphylococcus aureus with septicemia and pericarditis cured without surgery by iodo-sulfonamide therapy.

Archives francaises de pediatrie·2010

Same journal

Mickulicz syndrome and hepatomegaly during a diabetes mellitus.

Archives francaises de pediatrie·2010

See all related articles

This study details a 14-year-old boy with short stature, eczema, and recurrent infections, showing persistent antibody deficiency despite normal T and B cell counts. A prolonged immune system maturation delay is suggested.

Area of Science:

Immunology
Pediatrics
Clinical Case Study

Background:

Presents a case of a 14-year-old male with intrauterine growth retardation.
Initial symptoms included short stature, generalized eczema, and recurrent infections.

Observation:

Hypogammaglobulinemia with antibody deficiency was noted in early childhood.
Infections became less severe over time.
Normal plasma levels of IgA, IgG, IgM, and IgE were observed, contrasted with hyperimmunoglobulinemia D.

Findings:

Persistent deficiency of antibodies against tested antigens.
Normal T and B lymphocyte counts and in vitro proliferation responses.
Abnormal helper T cell/suppressive T cell activity ratio noted.

Related Experiment Videos

Implications:

Suggests a prolonged immune system maturation delay possibly linked to fetal hypotrophy.
Highlights a complex immunodeficiency with specific antibody production defects.
Underscores the importance of detailed immunological assessment in cases of recurrent infections and growth issues.