An outbreak of Cotyledon orbiculata L. poisoning in a flock of Angora goat rams

An acute outbreak of C. orbiculata L. poisoning in a flock of 16 Angora Goat rams is described. Typical signs of acute bufadienolide cardiac glycoside toxicity were manifested and 6 animals died. In the 2 animals examined histopathologically multiple foci of myocardial degeneration and necrosis were present. Treatment consisted, inter alia, of drenching with a mixture of activated charcoal, potassium chloride and a commercial preparation, Universal Antidote (Centaur) and parenteral administration of atropine sulphate.