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Related Experiment Videos

Mazindol for nocturnal enuresis.

R C Tiptaft, C R Woodhouse, D F Badenoch

    British Journal of Urology
    |December 1, 1984
    PubMed
    Summary

    Mazindol effectively treated adult enuresis in patients resistant to conventional therapies. Most participants achieved dryness, with significant improvement noted in others, indicating mazindol

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    Area of Science:

    • Urology
    • Pharmacology
    • Pediatric Medicine

    Background:

    • Adult enuresis presents a persistent challenge, often inadequately managed by standard treatments.
    • Refractory enuresis necessitates exploring alternative therapeutic agents.

    Purpose of the Study:

    • To evaluate the efficacy of mazindol in adult patients with enuresis unresponsive to conventional therapies.
    • To assess the clinical outcomes of mazindol treatment for persistent enuresis.

    Main Methods:

    • A cohort of sixteen adult enuretic patients, previously treated unsuccessfully, received mazindol.
    • Patient response was monitored to quantify treatment effectiveness.

    Main Results:

    • Sixty-three percent of patients achieved complete dryness.
    • An additional thirty-one percent experienced significant improvement in their enuretic symptoms.
    • Mazindol demonstrated a high success rate in this refractory group.

    Conclusions:

    • Mazindol is a promising therapeutic option for adult enuresis.
    • This study supports the use of mazindol for enuretic individuals who have not responded to conventional treatments.

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