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Related Experiment Videos

Amniotic fluid infection at term.

D L Woods, C C Sinclair-Smith, A F Malan

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |January 28, 1978
    PubMed
    Summary
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    Amniotic fluid infection is common (52%) in term deliveries, often without clinical signs in newborns. This suggests localized colonization rather than widespread fetal infection.

    Area of Science:

    • Obstetrics and Gynecology
    • Neonatal Medicine
    • Pathology

    Background:

    • Amniotic fluid infection (AFI) is a significant complication in term deliveries.
    • Early detection and understanding of AFI are crucial for neonatal outcomes.

    Purpose of the Study:

    • To determine the incidence of amniotic fluid infection in term deliveries.
    • To evaluate diagnostic methods for AFI, including placental histology and gastric aspirate cytology.
    • To explore correlations between maternal factors, infant characteristics, and inflammatory responses in AFI.

    Main Methods:

    • Histological examination of placenta and umbilical cord for inflammatory markers.
    • Cytological examination of neonatal gastric aspirate for infection indicators.
    • Utilized a detailed histological grading system for inflammatory response.

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    Main Results:

    • High incidence of amniotic fluid infection (52%) observed in term deliveries.
    • No significant relationship found between maternal nutrition, infant weight, and histological inflammatory response.
    • Gastric aspirate cytology showed limited diagnostic value for infection.

    Conclusions:

    • Amniotic fluid infection is prevalent in term pregnancies.
    • Histological findings suggest localized amniotic fluid colonization may occur without apparent fetal spread.
    • Clinical assessment alone may underestimate the incidence of subclinical amniotic fluid infection.