Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Collection and analysis of pedigree data.

D E Goldgar

    Birth Defects Original Article Series
    |January 1, 1984
    PubMed
    Summary

    Computerized pedigree databases streamline genetic data collection and analysis. These systems aid in understanding disease mechanisms and improving genetic counseling for at-risk individuals.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Association of gene variant type and location with breast cancer risk in the general population.

    Annals of oncology : official journal of the European Society for Medical Oncology·2025
    Same author

    Assessing biases of information contained in pedigrees for the classification of BRCA-genetic variants: a study arising from the ENIGMA analytical working group.

    Hereditary cancer in clinical practice·2016
    Same author

    Multigene testing of moderate-risk genes: be mindful of the missense.

    Journal of medical genetics·2016
    Same author

    Tumour morphology predicts PALB2 germline mutation status.

    British journal of cancer·2013
    Same author

    Rare mutations in XRCC2 increase the risk of breast cancer.

    American journal of human genetics·2012
    Same author

    Cannabis, tobacco and domestic fumes intake are associated with nasopharyngeal carcinoma in North Africa.

    British journal of cancer·2009

    Area of Science:

    • Genetics
    • Bioinformatics
    • Medical Informatics

    Background:

    • Pedigree data is crucial for understanding genetic disorders.
    • Traditional methods of pedigree data management can be inefficient.
    • Computerized systems offer enhanced capabilities for handling complex genetic information.

    Purpose of the Study:

    • To highlight the utility of computerized database systems for pedigree data.
    • To demonstrate the application of these systems in genetic research and analysis.
    • To emphasize their role in improving genetic counseling.

    Main Methods:

    • Utilizing computerized database systems for routine pedigree data collection and display.
    • Employing segregation and linkage analysis for genetic research.
    • Integrating research data into genetic analysis programs.

    Main Results:

    • Computerized systems facilitate efficient data management and retrieval.
    • Segregation and linkage analyses provide insights into genetic and environmental factors of disorders.
    • These analyses are foundational for discovering biochemical bases of diseases.

    Conclusions:

    • Computerized pedigree databases are valuable tools for both research and clinical applications.
    • Genetic analysis methods, supported by these databases, enhance our understanding of disease etiology.
    • Improved genetic insights lead to more precise counseling for individuals at genetic risk.

    Related Experiment Videos