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[Ganglioneuroma and chronic secretory diarrhea]
Arquivos De Gastroenterologia
|October 1, 1984
Insights
A rare VIP-secreting ganglioneuroma caused severe chronic diarrhea in a child. Surgical removal was necessary after complex diagnostics, highlighting this rare tumor
Area of Science:
- Pediatric Gastroenterology
- Surgical Oncology
- Endocrinology
Background:
- Chronic diarrhea in children presents diagnostic challenges.
- Ganglioneuromas are rare neuroblastic tumors, occasionally functioning.
Observation:
- A 6-year-old child presented with 2 years of severe watery chronic diarrhea.
- Extensive investigations were performed, including exploratory abdominal surgery.
Findings:
- A VIP (vasoactive intestinal polypeptide)-secreting ganglioneuroma was identified as the cause.
- The tumor's role in the severe, prolonged diarrhea was confirmed.
Implications:
- This case underscores the importance of considering rare neuroendocrine tumors in refractory pediatric diarrhea.
- Understanding VIP-secreting tumors is crucial for diagnosis and management.
- Highlights the complexity of diagnosing and surgically managing rare pediatric abdominal tumors.
Abstract:
The clinical case of a six year old child with two years of severe watery chronic diarrhea is presented. An exhaustive investigation followed by exploratory abdominal surgery, showed ganglioneuroma secreting tumor of VIP (vasoactive intestinal polypeptide). The clinical behavior, the complexity of the diagnostic, its rareness and its physiopathology are discussed.