Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tissue polypeptide antigen immunoreactivity in human semen.

J Lizana, P Eneroth, M Bygdeman

    Archives of Andrology
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [An enigmatic eye in an enigmatic bust].

    Archivos de la Sociedad Espanola de Oftalmologia·2012
    Same author

    Mid-trimester induced abortion: a review.

    Human reproduction update·2006
    Same author

    Effects of progestogens on endometrial maturation in the implantation phase.

    Ernst Schering Research Foundation workshop·2005
    Same author

    Effects of misoprostol on uterine contractility following different routes of administration.

    Human reproduction (Oxford, England)·2003
    Same author

    Improving cycle control in progestogen-only contraceptive pill users by intermittent treatment with a new anti-progestogen.

    Human reproduction (Oxford, England)·2002
    Same author

    Evidence for target-specific outgrowth from subpopulations of grafted human dopamine neurons.

    Microscopy research and technique·2001
    Same journal

    The benefits and limitations of the sperm quality analyzer IIB in assessing porcine sperm motility.

    Archives of andrology·2008
    Same journal

    An exploratory study of the effects of 12 month administration of the novel long-acting testosterone undecanoate on measures of sexual function and the metabolic syndrome.

    Archives of andrology·2008
    Same journal

    Effect of sperm preparation techniques by density gradient on intra-individual variation of sperm motility.

    Archives of andrology·2008
    Same journal

    Spermatoceles in adults: when does size matter?

    Archives of andrology·2008
    Same journal

    Testicular microlithiasis in Taiwanese men.

    Archives of andrology·2008
    Same journal

    Sperm preparation: DNA damage by comet assay in normo- and teratozoospermics.

    Archives of andrology·2008
    See all related articles

    Tissue polypeptide antigen (TPA) is found in human seminal plasma and is absorbed by sperm. Studies suggest TPA originates from the prostate and is not linked to sperm quality or infertility.

    Area of Science:

    • Reproductive biology
    • Onco-immunology

    Background:

    • Tissue polypeptide antigen (TPA) is a tumor-associated marker.
    • TPA presence and origin in human seminal plasma are not well-understood.

    Purpose of the Study:

    • To investigate the presence, origin, and characteristics of TPA in human seminal plasma.
    • To determine the correlation between seminal plasma TPA levels and sperm parameters or infertility.

    Main Methods:

    • Immunological assays to detect TPA in seminal plasma.
    • Split-ejaculate studies to determine TPA origin.
    • Correlation analysis with sperm count, motility, and morphology.

    Main Results:

    • TPA immunoreactivity was detected in human seminal plasma, showing similarity to tumor-derived TPA.

    Related Experiment Videos

  • TPA is taken up by spermatozoa and appears to originate mainly from the prostate.
  • Seminal plasma TPA levels were not correlated with sperm count, motility, or morphology.
  • No significant difference in TPA levels was observed between normozoospermic individuals and those undergoing infertility investigations.

    • Conclusions:

    • Human seminal plasma contains TPA, likely originating from the prostate.
    • TPA uptake by spermatozoa suggests a potential interaction with reproductive cells.
    • Seminal plasma TPA levels do not appear to be a reliable indicator of male fertility or infertility.