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Angiosarcomas in hamsters after inoculation of brain tissue from a case of progressive multifocal leukoencephalopathy
Cancer
|April 15, 1984
Abstract:
Subcutaneous inoculation of minced brain tissue from a case of progressive multifocal leukoencephalopathy into newborn Syrian hamsters produced transplantable angiosarcomas in 2 of 11 animals. Immunostaining revealed the presence of SV40 in the progressive multifocal leukoencephalopathy (PML) tissue, indicating this virus as the tumor-inducing agent.
