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Preparation and properties of mouse monoclonal antibody (W14A) to human chorionic gonadotropin

F Searle, C S Partridge, A Kardana

    International Journal of Cancer
    |April 15, 1984
    PubMed

    A mouse monoclonal antibody, W14A, has been prepared which reacts with intact human chorionic gonadotropin and its beta-subunit, showing less than 2% cross-reactivity towards the alpha-subunit and 0.5% cross-reactivity towards the beta-subunit of luteinizing hormone. The reagent is suitable for the radioimmunolocalization of choriocarcinoma and trophoblastic teratoma in humans. A preliminary radioimmunoassay has been developed.

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