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Related Experiment Videos

Perianal orf.

C T Kennedy, A Lyell

    Journal of the American Academy of Dermatology
    |July 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Orf virus (parapoxviral infection) can present atypically in children, especially in occluded perineal areas. Electron microscopy confirmed the diagnosis in two challenging pediatric cases.

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    Area of Science:

    • Veterinary Virology
    • Human Infectious Diseases
    • Dermatology

    Background:

    • Orf virus (parapoxviral infection) is a zoonotic disease typically affecting sheep and goats.
    • Diagnosis is usually straightforward with characteristic skin lesions and a history of animal contact.
    • Atypical presentations can complicate diagnosis, particularly in pediatric populations.

    Observation:

    • Two cases of orf presented in a perineal location in young children.
    • The perineal location, a flexural and occluded site, modified the typical physical signs of the infection.
    • Standard diagnostic methods were challenged by the atypical presentation.

    Findings:

    • Electron microscopy of lesion scrapings was crucial for establishing the diagnosis.
    • This highlights the utility of electron microscopy in confirming orf when clinical signs are ambiguous.

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  • The study demonstrates that orf can manifest with altered morphology in specific anatomical locations.

    • Implications:

    • Clinicians should consider orf in the differential diagnosis of perineal lesions in children, even without a clear history of sheep contact.
    • Electron microscopy serves as a valuable tool for diagnosing challenging orf cases.
    • Understanding atypical presentations improves early detection and management of zoonotic viral infections in children.