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Murine leukemia L1210 cell lines with different patterns of resistance to platinum coordination complexes
Cancer Treatment Reports
|September 1, 1984
Abstract:
A murine leukemia L1210 cell line has been developed that exhibits 30-fold resistance to 1,2-diaminocyclohexaneplatinum(II) analogs but retains sensitivity to cisplatin. This contrasts existing cell lines which exhibit the opposite pattern of resistance. Both cell lines retain their sensitivity to melphalan.