[Pancreatic exocrine secretion in cancer of the pancreas]

Pancreatic exocrine secretion was studied in 22 patients with pancreas cancer. In 17 of patients the diagnosis was made at operation. In all patients examined the pancreocymine-secretin test according to Herfort was performed. The results were compared with those of a control group of 30 healthy subjects. In 95.5 per cent of the examined a statistically significant decreased hydrobicabonate and enzyme secretion was found. The changes in the pancreatic secretion are characterized by the presence of a total secretory deficiency, with a significant diminution ( p less than 0.001) of all parameters of pancreatic secretion.