Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nifedipine relieves exercise-exacerbated myalgias.

R L Sufit, H A Peters

    Muscle & Nerve
    |October 1, 1984
    PubMed
    Summary

    Nifedipine, a calcium channel blocker, effectively treated exercise-induced muscle pain in three women when other medications failed. Side effects were dose-dependent, limiting full symptom relief.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Consumption rates and food preferences of slugs in a calcareous grassland under current and future CO<sub>2</sub> conditions.

    Oecologia·2017
    Same author

    Lack of association of VEGF promoter polymorphisms with sporadic ALS.

    Neurology·2006
    Same author

    Paraoxonase cluster polymorphisms are associated with sporadic ALS.

    Neurology·2006
    Same author

    Clinical relevance of biologic factors in male breast cancer.

    Breast cancer research and treatment·2001
    Same author

    High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer.

    Cancer research·2001
    Same author

    The urokinase-type plasminogen activator system in resected non-small-cell lung cancer. Rotterdam Oncology Thoracic Study Group.

    Annals of oncology : official journal of the European Society for Medical Oncology·2000

    Area of Science:

    • Exercise physiology
    • Pharmacology
    • Neurology

    Background:

    • Exercise-exacerbated myalgias can be debilitating.
    • Standard treatments for refractory myalgias are often ineffective.

    Observation:

    • Three women presented with severe exercise-induced muscle pain.
    • These symptoms persisted despite conventional pharmacotherapy.

    Findings:

    • Nifedipine, a calcium channel blocker, demonstrated a favorable response in alleviating myalgias.
    • Treatment was associated with dose-related side effects, impacting overall efficacy.
    • Potential mechanisms for nifedipine's action on myalgias were proposed.

    Implications:

    • Nifedipine may represent a novel therapeutic option for refractory exercise-exacerbated myalgias.
    • Further research is warranted to optimize nifedipine dosage and minimize side effects.
    • Understanding the underlying mechanisms could lead to targeted therapies.

    Related Experiment Videos