Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Craniofacial dysmorphism and opsoclonus.

J R Coppeto, M L Monteiro

    Ophthalmic Paediatrics and Genetics
    |December 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    This case study details a patient with craniofacial dysmorphism and opsoclonus, a rare neurological disorder. The condition, linked to delayed brainstem inhibitory cell maturation, resolved by 18 months.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Prospective multicentre study on antibiotic resistance of Helicobacter pylori strains obtained from children living in Europe.

    Gut·2006
    Same author

    Superior orbital 'petrositis' and late ischaemic monocular blindness induced by intense UV radiation exposure.

    Occupational medicine (Oxford, England)·2002
    Same author

    Spontaneous regression of optic gliomas: thirteen cases documented by serial neuroimaging.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2001
    Same author

    Ocular myositis and diffuse meningoencephalitis from Trypanosoma cruzi in an AIDS patient.

    Transactions of the Royal Society of Tropical Medicine and Hygiene·2000
    Same author

    Meningiomas involving the parasellar region.

    Acta neurochirurgica. Supplement·1996
    Same author

    Fabry's disease in a female carrier with bilateral thalamic infarcts: a case report and a family study.

    Sao Paulo medical journal = Revista paulista de medicina·1994
    Same journal

    Ocular growth in infant aphakia. Bilateral versus unilateral congenital cataracts.

    Ophthalmic paediatrics and genetics·1993
    Same journal

    Butterfly-shaped macular dystrophy. Longitudinal case study of two siblings.

    Ophthalmic paediatrics and genetics·1993
    Same journal

    A variant of central areolar choroidal dystrophy.

    Ophthalmic paediatrics and genetics·1993
    Same journal

    North Carolina macular dystrophy (MCDR1). A review and refined mapping to 6q14-q16.2.

    Ophthalmic paediatrics and genetics·1993
    Same journal

    To lump or to split?

    Ophthalmic paediatrics and genetics·1993
    Same journal

    Ligneous conjunctivitis. Ten years follow-up.

    Ophthalmic paediatrics and genetics·1993
    See all related articles

    Area of Science:

    • Neurology
    • Pediatrics
    • Genetics

    Background:

    • Opsoclonus is a rare neurological disorder characterized by involuntary, rapid, conjugate eye movements.
    • Craniofacial dysmorphism encompasses a range of congenital anomalies affecting the skull and face.
    • The co-occurrence of opsoclonus and craniofacial anomalies presents a diagnostic and etiological challenge.

    Observation:

    • A neonate presented with significant craniofacial dysmorphism and the onset of opsoclonus.
    • The opsoclonus symptoms were noted from the perinatal period and gradually subsided by 18 months of age.
    • A review of prior literature revealed a limited number of cases associating opsoclonus with cranial and facial abnormalities.

    Findings:

    • The authors propose that the opsoclonus in this case was associated with delayed maturation of inhibitory cells within the brainstem.

    Related Experiment Videos

  • This hypothesis suggests a potential neurodevelopmental basis for opsoclonus in conjunction with craniofacial anomalies.
  • The case highlights the variability in presentation and resolution of opsoclonus.

    • Implications:

    • Understanding the neurobiological underpinnings of opsoclonus in dysmorphic syndromes can aid in diagnosis and management.
    • Further research into brainstem development and its relation to ocular motor control is warranted.
    • This case contributes to the limited case reports on opsoclonus associated with congenital craniofacial abnormalities.