Acetylcholinesterase (E.C.3.1.1.7) in the skeletal muscle and brain of rats after exercise and long-term training

The activity of acetylcholinesterase was determined in the skeletal muscle and brain of rats after one exercise (running) and after long-term training of definite programme. Enzyme activity was determined by the colorimetric method of Hestrin. The results were subjected to statistical analysis by the t test of Student. An increase was demonstrated in AChE activity after one exercise in both tissues, but only in the muscle this increase was statistically significant. After long-term training the direction of this change was reversed. In the muscle the decrease was statistically significant, while the change in the brain was not significant.