Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A multipoint micro antimony pH electrode for tissue surface measurements.

N Lund, F Sjöberg, H Guldbrand

    International Journal of Clinical Monitoring and Computing
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Overexpression of VEGFα as a biomarker of endothelial dysfunction in aortic tissue of α-GAL-Tg/KO mice and its upregulation in the serum of patients with Fabry's disease.

    Frontiers in cardiovascular medicine·2024
    Same author

    Very-high-frequency oscillations in the main peak of a magnetar giant flare.

    Nature·2021
    Same author

    Sprayed cultured autologous keratinocytes in the treatment of severe burns: a retrospective matched cohort study.

    Annals of burns and fire disasters·2020
    Same author

    More precise phenotyping of cluster headache using prospective attack reports.

    European journal of neurology·2019
    Same author

    Early BCG Vaccination, Hospitalizations, and Hospital Deaths: Analysis of a Secondary Outcome in 3 Randomized Trials from Guinea-Bissau.

    The Journal of infectious diseases·2018
    Same author

    Algorithm for sorting chromosomal aberration data.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2017
    Same journal

    Computerized monitoring of potentially interfering medication in thyroid function diagnostics.

    International journal of clinical monitoring and computing·1998
    Same journal

    Retest-reliability and convergent validity of noninvasive blood pressure determination: arm sphygmomanometry vs. Peñaz-method.

    International journal of clinical monitoring and computing·1998
    Same journal

    Respiratory sinus arrhythmia during anaesthesia: assessment of respiration related beat-to-beat heart rate variability analysis methods.

    International journal of clinical monitoring and computing·1998
    Same journal

    Auscultation revisited: the waveform and spectral characteristics of breath sounds during general anesthesia.

    International journal of clinical monitoring and computing·1998
    Same journal

    Design and implementation of a PC-based data acquisition system for measuring ECG and respiratory signals.

    International journal of clinical monitoring and computing·1998
    Same journal

    The inspiratory to end-tidal oxygen difference during exercise.

    International journal of clinical monitoring and computing·1998
    See all related articles

    Researchers developed a multipoint tissue surface pH electrode using monocrystalline antimony. This new sensor allows for more detailed monitoring of tissue acid-base status, revealing acidosis during microcirculation shutdown.

    Area of Science:

    • Biomedical Engineering
    • Physiological Measurement
    • Materials Science

    Background:

    • Accurate tissue pH monitoring is crucial for understanding physiological states.
    • Existing methods may lack the spatial resolution for detailed surface measurements.
    • Antimony electrodes are established for pH sensing but require careful calibration and consideration of environmental factors.

    Purpose of the Study:

    • To develop and evaluate a novel multipoint tissue surface pH electrode.
    • To assess the electrode's performance in monitoring acid-base status under various physiological conditions.
    • To investigate the influence of oxygen levels on antimony electrode potential in vivo.

    Main Methods:

    • Fabrication of a multipoint pH electrode from monocrystalline antimony, integrated with an MDO oxygen electrode.

    Related Experiment Videos

  • Standardization in TRIS buffers at 37°C and simultaneous registration of tissue oxygen pressure.
  • In vivo studies on rabbits under normal, hypoxic, hypocapnic, hypovolemic, and hyperoxic conditions.

    • Main Results:

    • The multipoint antimony electrode successfully measured tissue surface pH in rabbits, ranging from 7.0 to 7.4 in normal states.
    • Tissue acidosis and scattered pH values were observed during microcirculation shutdown (hypocapnic and hypovolemic states).
    • The oxygen correction factor determined in vitro appeared applicable in vivo, though further validation is needed.

    Conclusions:

    • The developed multipoint pH sensor provides enhanced and detailed monitoring of tissue acid-base status.
    • The electrode is capable of detecting changes in tissue pH associated with altered physiological conditions.
    • This technology holds promise for improved understanding and management of critical care situations.